What is the correct pediatric Amiodarone dose for cardiac arrest?

For pediatric patients experiencing cardiac arrest, the administration of Amiodarone is critical for the management of certain arrhythmias. The correct dosing for Amiodarone in this context is 5 mg/kg administered via intravenous (IV) or intraosseous (IO) routes, and this is subject to a maximum limit of 300 mg.

This dosing is based on evidence and practice guidelines that aim to provide effective antiarrhythmic therapy while minimizing the risk of potential side effects from excessive dosing. The rationale for the specific dosage is to ensure that children receive an appropriate therapeutic amount that is effective for stabilizing their cardiac rhythm during a critical situation.

The maximum limit helps prevent any adverse effects associated with high doses of Amiodarone, ensuring that while the treatment is potent enough to address the life-threatening arrhythmia, it remains within a safe range for pediatric patients, who can be particularly sensitive to medication dosages. The other options do not align with these established guidelines, either by providing a lower dosage that may be insufficient or a higher maximum that could lead to harmful effects.